BANP Antikörper (AA 30-390)
Kurzübersicht für BANP Antikörper (AA 30-390) (ABIN6242199)
Target
Alle BANP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 30-390
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Aufreinigung
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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Immunogen
- This BANP antibody is generated from a mouse immunized with a recombinant protein between 30-390 amino acids from human BANP.
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Isotyp
- IgG1 kappa
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Applikationshinweise
- WB: 1:1000. IHC-P: 1:25
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- BANP (Protein BANP (BANP))
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Andere Bezeichnung
- BANP
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Hintergrund
- Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).
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Molekulargewicht
- 56494
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UniProt
- Q8N9N5
Target
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